Prediction Analysis for Microarrays, for the R package
R functions for PAM- software for carrying out sample classification from gene
by the method of nearest shrunken centroids.
You don't need to be familiar with R to start using PAM.
What is R?
PAM is a simple, accurate and fast classifier, providing interpretable results for the biologist.
It has many novel features, including "heterogeneity analysis" for discriminating
a diseased group from a normal one.
The methodology is described in Tibshirani, Hastie,
Narashiman and Chu (2002):
of multiple cancer types by shrunken centroids of gene expression"
. PNAS 2002 99:6567-6572 (May 14).
What is nearest shrunken centroids?
Some sample plots from PAM
PAM works under Windows and Unix/Linux.
We have not yet tried our software on a Mac: R software is still evolving
for the Mac. Given a working version of R, there is no reason why PAM
Installation guide and manual.
MAC OS X binary